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    The accurate DNA structure  〜from JAPAN〜

    created by SICP__DNA on 2013.01.10

    Main Section
    We could build a DNA model with LEGOs, which is both beautiful and accurate!
    A model that had cleared all scientific points.

    OUR BELIEF
    Characteristics of DNA are suitable for LEGO. This is why people all over the world challenge themselves to build DNA models with LEGOs.
    In terms of scientific accuracy, it is more important to focus on each
    fundamental part. Constructing the form of the parts correctly should naturally lead to the DNA structure, which is beautiful as well as accurate.

    CONCEPTS
    During the process of constructing a DNA model with LEGO bricks,
    one can learn the structure of DNA.


    Here is a link to a video of this model.
    YouTube

     DNAはすべての生物の遺伝物質の本体。長い鎖状の生体高分子だ。たった4種類(塩基)の分子が、どのような順番でどのくらいの長さで並んでいるかが多様な生きものの違いとなる。
     美しくシンプルなDNAの構造は右巻きの2重らせん。DNAの構造発見(1953年)から60年経った現在でも、手にとってじっくり観察できる手頃な模型は発売されていない。DNAの構造は中心軸自体が回転していて、自立する構造を再現しにくいことも原因のひとつ。
     今回の模型は大学の授業でも使えるレベルの正確さで再現されている。もちろん組み立てるだけでも楽しく美しい仕上がり。このレゴを組み立てるだけで、その後の学習は楽勝!?のちのち学ぶことになるDNAを遊びで習得!!

    動画はこちらから!
    YouTube

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    In detail Point
    ・ the clockwise double helix structure
    ・ 1 turn is 10steps.
    ・ Ratio → Breadth(2nm) : Length (1turns=3.4nm)
    ・ Having Major grooves and Minor Groove. 
    ・ The Each direction of Sugar (chemical polarity) is reversed.

    再現ポイント:
    ・ 10段で一回転する右巻きのらせん構造
    ・ 幅2nm:高さ(10段)3.4nmの幅と高さの比。
    ・ 大きな溝と小さな溝
    ・ 両鎖の糖の向きが逆

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    ・ Four DNA bases (A, T, G, C)
    ・ Purine base is bigger than pyrimidine base. (A & G : purine, T & C : pyrimidine.)
    ・ Base pairs between the two strands: A with T and G with C
    ・ A with T bonds are 2 hydrogen bonds, G with C bonds are 3 hydrogen bonds.

    ・ 4種類の塩基(ATGC)とその大きさ:ピリミジン塩基(T/C)とプリン塩基(A/G)
    ・ AはTとGはCとしか結合できない
    ・ 塩基ペアの水素結合の数A-Tは2本 G−Cは3本

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    WHAT IS MORE !
    ! OPENS !
    You can learn a mechanism for heredity.

    らせん構造を組み立てた後に、両端を持って手を広げると、鎖がほどけて1本鎖に!
    DNAの複製(遺伝)の学習も可能です!


    BACKGROUND
     Over 50 years have passed since the discovery of the DNA structure. Many
    attempts have been made to build DNA models using LEGO bricks. They seem to have succeeded to represent the beautiful double helix structure, but none of them are scientifically accurate.
     Therefore we propose a new LEGO model of DNA, which is scientifically accurate.
     While this model maintains the unique quality of LEGO bricks, it can be used by students to learn about the structure of DNA.
     In other words, our model has great potential to be used as a teaching aid
    in the classroom.
    The bricks can be put together, taken apart and put together again!

    Furthermore …..
    The structure of DNA Provides a Mechanism for Heredity.
    Hence it is very important to understand the structure.

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